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Wham clusters the many prospect breakpoints and rounds their positions to the nearest tenth foundation pair. The place with the best examine support is claimed. When the soft-clipped consensus sequence is often aligned into the putative breakpoint area using the Smith-Waterman algorithm, the breakpoint is more refined to The situation of the consen

Wham is made for paired-conclude Illumina libraries with common insert measurements (~300bp-500bp). Wham integrates mate-pair mapping, split examine mapping, comfortable-clipping, option alignment and consensus sequence centered evidence to predict SV breakpoints with one-nucleotide precision. Wham generates a merged pileup (catalog of reads maskin

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